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Bioma Hormone Balance bottle

Is your “estrobolome” making menopause symptoms worse?

When you restore your estrogen-regulating gut bacteria:

  • Night sweats and hot flashes ease

  • Mood swings and fatigue lift

  • Extra weight and joint pain fade

  • Intimacy feels comfortable again

  • Scientific ingredients

  • Vegan

  • Non-GMO

  • Stimulant-free

  • Keto-friendly

  • Gluten-free

  • Scientific ingredients

  • Vegan

  • Non-GMO

  • Stimulant-free

  • Keto-friendly

  • Gluten-free

Start by selecting your menopause stage:

Perimenopause

Menopause

Postmenopause

Not sure

Start restoring your “estrobolome”

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$0.87 PER DAY
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Best value SAVE 50%
6-month supply

+SECRETGIFT

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For achieving sustainable results

$77.98

$38.99

per bottle

180 SERVINGS
$1.30 PER DAY
6 BOTTLES DELIVERED
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3-month supply

+SECRETGIFT

3-month supply

Great for building new habits

$76.65

$45.99

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90 SERVINGS
$1.53 PER DAY
3 BOTTLES DELIVERED
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1-month supply
1-month supply

Ideal solution for trying out

$97.13

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It all starts with your “estrobolome”

What standard remedies do

  • Add estrogen from outside

  • Manage one symptom at a time

  • Need a prescription

  • Require medical monitoring

  • Leave your “estrobolome” disrupted

What Hormone Balance does

  • Works with the estrogen you make

  • Addresses the shared root cause

  • No prescription

  • Two capsules a day

  • Restores your “estrobolome”

Your “estrobolome” is the subset of gut bacteria that decides whether estrogen gets recycled back into circulation or excreted. Hormone Balance works on two tracks at once. Five clinically studied probiotic strains at 14 billion CFU, plus 300mg of FOS prebiotic, rebuild the bacteria your “estrobolome” depends on. Alongside them, five plant phytoestrogens act like the estrogen your body is missing, so you get relief in the weeks before the restoration takes hold. Two delayed-release capsules a day with your largest meal.

Because they weren’t built to. Hormone therapy adds estrogen from outside your body — it doesn’t change how your gut handles the estrogen you already make. Non-hormonal medications manage individual symptoms one at a time. Your “estrobolome” is sensitive. Stress, medications, processed food, alcohol, sugary drinks, and ageing all disrupt it. Hormone Balance was formulated from the ground up to restore it — and to keep you comfortable while it does.*

*Individual results vary with health history, hormonal profile, and gut microbiota baseline. Hormone Balance is not a replacement for prescribed medication. Talk to your doctor before combining it with hormone therapy.

Estrobolome improvement over 60 days: Bioma vs typical remedies

What's inside your Hormone Balance bottle

Rebuild your “estrobolome” at the source

Five clinically studied strains at 14 billion CFU. B. longum BB-536® drives estrogen recycling through β-glucuronidase activity, while L. acidophilus La-14® supports “estrobolome” function and vaginal pH.

Support mood and menopausal weight through the gut

L. rhamnosus HN001® works on the gut-brain axis, linked in research to reduced anxiety and low mood. L. gasseri SBT-2055 is clinically studied for reducing abdominal fat — the fat that shifts as estrogen falls.

Feed your “estrobolome” so it stays

300mg of fructo-oligosaccharides, the highest prebiotic dose in the Bioma range. Probiotics that arrive without food pass straight through. FOS feeds the strains your “estrobolome” is built from so they survive, multiply, and hold.

Ease the digestive side of menopause

Bloating and irregular digestion are among the first things menopause changes, and the first things most women notice improving. FOS supports smoother digestion, usually inside the first week.

One of the most potent plant estrogens known

You wouldn’t expect hops in a menopause formula. But its 8-prenylnaringenin (8-PN) works on estrogen receptors to ease hot flashes and night sweats.

Quieter evenings, better nights

Hops has a calming, mood-steadying effect alongside its estrogenic activity. It supports the emotional side of menopause and the 2am wake-ups that come with night sweats.

The traditional answer to hot flashes

Black cohosh has been used for generations for vasomotor symptoms — the hot flashes and night sweats that hit hardest. Its mild estrogenic activity helps reduce the discomfort of hormonal swings.

Why it isn’t enough on its own

Most menopause supplements stop at black cohosh. It’s a genuine phytoestrogen, but it does nothing for the “estrobolome” underneath. Here it’s one of five, on top of a probiotic and prebiotic foundation.

Plant compounds your body reads as estrogen

Genistein and daidzein are the two primary soy isoflavones, at 40mg each. They mimic estrogen closely enough to help with hot flashes, mood swings, and vaginal dryness — without adding hormones.

Relief while your “estrobolome” rebuilds

Restoring an “estrobolome” takes around 12 weeks. Phytoestrogens work far faster. That’s why this formula is dual-action: the isoflavones cover the early weeks while the probiotics do the slower work underneath.

Bioma Hormone Balance bottle

Why women choose Hormone Balance

Bioma Hormone Balance

Hormone Balance

Standard menopause supplements

Standard menopause supplements

Restores your “estrobolome”

5 plant estrogens

5 strains, 14B CFU

300mg prebiotic

Delayed release

Supports digestion

Lab tested

Ingredients with proven benefits

Every serving delivers a dual-action formula — 14 billion CFU across five clinically studied probiotic strains and 300mg of FOS prebiotic to restore your “estrobolome”, plus five plant phytoestrogens including flaxseed lignans and red clover isoflavones for relief in the meantime.

Approved by our customers

“Three weeks in and the night sweats went from every night to maybe twice a week. I’ll take it.”

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“I didn’t expect the bloating to go first. But it did, in about five days, and I hadn’t even been thinking about that.”

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“I’d never heard the word “estrobolome” before. Now I can’t believe nobody told me my gut had anything to do with this.”

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“I didn’t want to go on hormones. This felt like something I could actually just try.”

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“Two capsules with dinner. That’s the whole routine. After everything else I’ve tried, that’s what sold me.”

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“Three weeks in and the night sweats went from every night to maybe twice a week. I’ll take it.”

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“I didn’t expect the bloating to go first. But it did, in about five days, and I hadn’t even been thinking about that.”

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“I’d never heard the word “estrobolome” before. Now I can’t believe nobody told me my gut had anything to do with this.”

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“I didn’t want to go on hormones. This felt like something I could actually just try.”

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“Two capsules with dinner. That’s the whole routine. After everything else I’ve tried, that’s what sold me.”

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    Lactobacillus acidophilus La-14®, Lactococcus lactis Ll-23™, Lacticaseibacillus rhamnosus HN001™, Bifidobacterium lactis Bb-18™, Lactobacillus gasseri Lg-36™, Bifidobacterium longum Bl-05™

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Lose weight & power your gut

  • Supports gut bacteria growth
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  • Xylooligosaccharides (as iXOS™) (from Corn Cob)100 mg
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Improve hair, skin & nails

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  • Vitamin C (as Ascorbic Acid)50 mg
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Frequently asked questions

It’s the subset of your gut bacteria that regulates how estrogen is metabolised and recycled through your body. A balanced “estrobolome” reactivates the estrogen your ovaries still produce, keeping more of it in circulation. A disrupted one lets that estrogen leave your body instead.” → “Stress, medications, processed food, alcohol, sugary drinks, and ageing all disrupt it. Most menopause products don’t touch it — that’s the gap this formula was built for.

No. Hormone therapy adds estrogen your body didn’t produce. Hormone Balance is 100% hormone-free — it restores the gut bacteria that regulate your own estrogen, and provides plant compounds that act like it. Nothing synthetic, no prescription.

Gut comfort and less bloating usually come first, within about a week. Early improvements in hot flashes and sleep quality tend to show around two weeks. By weeks four to eight, most women notice a clear drop in how often hot flashes and night sweats happen. Full “estrobolome” restoration takes around 12 weeks.

Talk to your doctor before combining Hormone Balance with hormone therapy or any prescribed medication. It’s designed to fit alongside your routine, but your doctor has your full picture.

Genistein and daidzein are extracted isoflavones, not whole soy — the allergen proteins are removed, so the formula suits people avoiding soy as a food allergen. It’s also free from milk, eggs, fish, shellfish, tree nuts, peanuts, and sesame.

It’s formulated to support it. L. gasseri SBT-2055 is clinically studied for reducing abdominal fat and is included at 5 billion CFU specifically because estrogen decline drives fat toward the middle. A functioning “estrobolome” and the phytoestrogens support the same outcome from different directions.

You’re covered by our 14-day money-back guarantee. Every Bioma product is made in an FDA-registered, GMP-certified US facility — but if it isn’t right for you, you get your money back.

Hear our customers

I stopped dreading bedtime

The night sweats were the worst part. I'd wake up soaked at 2am, change, and lie there until five. I'd already tried a black cohosh supplement for three months and got almost nothing from it. This one is different, and I think it's because of the gut side — which I'd never heard of before. By week three I was waking once instead of three times. Now most nights I sleep through.

Linda R.

Verified Customer
Bioma Hormone Balance customer holding a bottle
I feel steady again

It wasn't the hot flashes that got me, it was the mood. I'd snap at my daughter over nothing and feel awful about it all day. I didn't want to go on hormones — my mother had a bad time with them. Six weeks in and I feel like there's a floor under me again. Same person, just not on a hair trigger.

Patricia L.

Verified Customer
The bloating went first, then everything else

I bought it for hot flashes and the first thing that changed was my digestion, which I hadn't even connected to menopause. About five days in. Then around week four I realised I hadn't had a flash at work in days. My jeans fit again too. Two capsules with dinner and that's it.

Sandra M.

Verified Customer
Four years postmenopause and it still helped

I assumed I'd missed the window. I'm 61, four years past my last period, and everything I read seemed aimed at women just starting out - I nearly didn't order. Hot flashes are down to a couple a week from several a day, and my energy is back in the afternoons. Wish I hadn't waited so long to try something.

Carol B.

Verified Customer

Look and feel like yourself again

Hormone-free, no prescription, two capsules a day. Restore the gut bacteria that regulate your estrogen — and the symptoms that come with it.

Bioma Health
© 2026 Bioma Health. All rights reserved.Disclaimer: Content and statements on this website have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. It should not be substituted for medical advice or medical intervention. Please consult a qualified healthcare provider when making medical decisions. Exercise and a healthy diet are necessary to achieve and maintain weight loss.