What is SIBO and How Does It Affect Your Digestion?

Small Intestinal Bacterial Overgrowth (SIBO) is a condition where there is an abnormal increase in the number of bacteria in the small intestine. While the large intestine naturally hosts a large number of bacteria, the small intestine typically has far fewer. When the balance of bacteria in the small intestine is disrupted, it can lead to digestive issues, discomfort, and nutrient malabsorption.
SIBO can affect digestion in a variety of ways, causing symptoms like bloating, gas, diarrhea, and constipation. In this article, we’ll explore what SIBO is, how it affects digestion, and how to manage it effectively.
What Causes SIBO?
SIBO occurs when there is an overgrowth of bacteria in the small intestine. Normally, the small intestine is home to a small amount of bacteria, while the majority of bacteria reside in the large intestine. However, several factors can lead to the growth of excess bacteria in the small intestine, including:
1. Dysfunctional Gut Motility
The small intestine relies on motility (the movement of food through the digestive tract) to clear out bacteria. If the movement of food through the small intestine is slowed or impaired (a condition known as intestinal dysmotility), bacteria can accumulate, leading to SIBO.
Scientific Source: Frontiers in Physiology – SIBO and Gut Motility
2. Structural Abnormalities
Certain structural issues in the small intestine can cause bacterial overgrowth. Conditions like ileocecal valve dysfunction, where the valve between the small and large intestine doesn’t close properly, can allow bacteria to move from the large intestine to the small intestine.
3. Immune System Impairment
The body’s immune system plays an essential role in controlling bacterial growth. If the immune system is compromised, it may be unable to effectively control bacteria in the small intestine, leading to SIBO.
4. Use of Certain Medications
Long-term use of certain medications, such as antibiotics or proton pump inhibitors (PPIs), can disturb the gut microbiome and increase the risk of SIBO.

Symptoms of SIBO
SIBO can present with a wide range of symptoms, many of which overlap with other digestive disorders like irritable bowel syndrome (IBS). Common symptoms of SIBO include:
- Bloating: A feeling of fullness and swelling in the abdomen, especially after meals.
- Gas: Excessive burping, flatulence, and discomfort due to the overgrowth of bacteria in the small intestine.
- Diarrhea: Frequent, loose stools often associated with SIBO.
- Constipation: Some individuals may experience constipation instead of diarrhea.
- Abdominal pain: Cramping or discomfort in the abdominal area.
- Nutrient malabsorption: SIBO can interfere with the absorption of nutrients, leading to vitamin deficiencies, weight loss, and fatigue.
- Unexplained weight loss: Due to malabsorption of nutrients.
How SIBO Affects Digestion
SIBO impacts the digestive process in multiple ways. The overgrowth of bacteria in the small intestine can interfere with digestion and the absorption of nutrients, leading to malnutrition and other complications.
1. Interference with Nutrient Absorption
When bacteria are overgrown in the small intestine, they can consume nutrients that the body needs. This leads to deficiencies in important vitamins and minerals, such as B12, iron, and folate. As a result, individuals with SIBO often experience fatigue, anemia, and weight loss.
2. Gas Production and Bloating
The excess bacteria in the small intestine ferment undigested food, producing gas as a byproduct. This gas leads to bloating, abdominal distention, and discomfort. Over time, this constant bloating can significantly impact quality of life.
3. Altered Gut Motility
SIBO often leads to slower gut motility, which means that food moves more slowly through the digestive tract. This slow transit allows bacteria to proliferate and can lead to further digestive problems like constipation or diarrhea.

Diagnosing SIBO
Diagnosing SIBO typically requires a combination of clinical evaluation and testing. The most common test used to diagnose SIBO is the lactulose breath test, which measures the levels of hydrogen and methane in the breath after consuming a sugar solution. Elevated levels of these gases indicate the presence of bacterial overgrowth in the small intestine.
Other tests for SIBO include:
- Small bowel aspirate and culture: Involves taking a sample from the small intestine to identify the number of bacteria.
- Imaging tests: These are used to rule out structural abnormalities, such as a hiatal hernia or intestinal strictures, that might contribute to SIBO.
Managing and Treating SIBO
The treatment of SIBO typically involves a combination of antibiotics, dietary modifications, and digestive support. Here are some of the most common approaches:
1. Antibiotics
The first line of treatment for SIBO is usually a course of antibiotics to reduce bacterial overgrowth. Common antibiotics used to treat SIBO include rifaximin and neomycin, which target the bacteria in the small intestine.
2. Dietary Changes: The Low-FODMAP Diet
A low-FODMAP diet is commonly recommended for individuals with SIBO. This diet eliminates foods that are high in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs), which can fuel bacterial growth and exacerbate symptoms.
3. Probiotics and Digestive Enzymes
In addition to antibiotics, probiotics and digestive enzymes can help improve gut health and digestive function. Probiotics help balance the gut microbiome by introducing beneficial bacteria, while digestive enzymes support the breakdown of food, reducing symptoms like bloating and gas.
Bioma Digestive Enzymes are designed to help break down proteins, fats, and carbohydrates more efficiently, supporting overall digestion and helping reduce SIBO-related discomfort. By improving digestion, Bioma Digestive Enzymes can also help alleviate symptoms such as bloating and abdominal pain.

Managing SIBO for Better Digestive Health
SIBO is a complex condition that requires a comprehensive treatment plan, including antibiotics, dietary changes, and digestive support. While the overgrowth of bacteria in the small intestine can significantly affect digestion, addressing it early with the right treatments can greatly improve symptoms and quality of life.
Bioma Digestive Enzymes can help manage SIBO symptoms by supporting gut health and aiding in the efficient digestion of food, helping to reduce bloating and discomfort.
Related articles


