Can Probiotics Help with Acid Reflux?

5 min read 2025 Jan 21
Written by Bioma Team

Acid reflux is one of those conditions that can turn an enjoyable meal into a miserable experience. The burning sensation, regurgitation, and discomfort associated with it often lead people straight to proton pump inhibitors (PPIs) or antacids for relief. But what if there was a way to manage acid reflux by addressing the gut microbiome itself? That’s where probiotics come in.

Probiotics have been extensively studied for their role in digestive health, and emerging research suggests they may help regulate some of the underlying factors contributing to GERD (gastroesophageal reflux disease). But how do they work? And which probiotic strains are most effective? Let’s get into it.

How Probiotics Might Help with Acid Reflux

Acid reflux often stems from gut dysbiosis—an imbalance of gut bacteria that affects digestion and increases gastric inflammation. A healthy gut microbiome supports proper digestion, reduces inflammatory proteins, and helps maintain esophageal pH levels.

Several mechanisms suggest that probiotics could help:

  • Regulating gut microbiome balance – The gut is home to trillions of bacteria, and an overgrowth of harmful microbes (such as H. pylori) can worsen reflux.
  • Supporting the mucosal barrier – Certain probiotic strains strengthen the lining of the stomach and esophagus, reducing gastric inflammation.
  • Preventing bloating and gas accumulation – A well-functioning microbiome helps prevent small intestinal bacterial overgrowth (SIBO), a condition linked to bloating and pressure on the stomach.
  • Improving esophageal motility – Some research indicates that probiotics help with food movement through the digestive tract, reducing the likelihood of acid reflux episodes.

A study published in Frontiers in Microbiology found that individuals with GERD had altered esophageal microbiota, suggesting that probiotics could play a role in restoring a healthy microbial environment.

Best Probiotic Strains for Acid Reflux

Not all probiotics are created equal. When it comes to acid reflux, some strains have been studied for their effects on reflux esophagitis, gut microbiome stability, and inflammation control.

Key probiotic strains include:

  • Lactobacillus acidophilus NCFM – Supports gut integrity and may reduce reflux severity.
  • Bifidobacterium lactis HN019 – Helps regulate digestion and promotes a balanced microbiome.
  • Bifidobacterium bifidum – Aids in strengthening epithelial cells and reducing gastric inflammation.
  • Saccharomyces boulardii – A yeast-based probiotic that has been shown to reduce H. pylori-related symptoms.
  • Bacillus subtilis – Supports overall gut resilience and helps combat dysbiosis.

Clinical studies have explored how these strains interact with the esophageal microbiome and gut health. A placebo-controlled intervention clinical trial found that patients taking Lactobacillus rhamnosus Rosell-11 and Bifidobacterium lactis Lafti B94 experienced less frequent reflux symptoms compared to those taking PPIs alone.

Probiotics vs. PPIs: Can They Work Together?

Many people rely on PPIs to reduce stomach acid, but long-term use can lead to unintended consequences, including nutrient deficiencies, gut dysbiosis, and increased risk of infections. This has led researchers to explore whether probiotics can be used alongside PPIs to mitigate these side effects.

For example, H. pylori eradication therapy, a common treatment for reflux-related conditions, often involves antibiotics and PPIs. Studies suggest that adding probiotic supplements like Lactobacillus acidophilus Rosell-52 may improve treatment outcomes and help prevent antibiotic-associated symptoms like diarrhea.

The Link Between Probiotics, Weight, and Acid Reflux

Weight plays a significant role in GERD and reflux symptoms. Excess weight can put pressure on the stomach, pushing acid into the esophagus. Interestingly, gut bacteria influence body composition, and probiotics may play a role in weight management.

  • Bifidobacterium species and Lactobacillus rhamnosus have been linked to healthier weight regulation.
  • A high-quality high-protein diet combined with probiotics may help improve metabolic syndrome, a condition often associated with GERD.
  • Prebiotics found in synbiotics (probiotics + prebiotics) support microbial diversity, which can influence digestion and weight.

Bioma Probiotics are formulated with strains that support digestion and metabolism, helping to address acid reflux from multiple angles.

Probiotics and Acid Reflux During Pregnancy

Pregnancy often comes with acid reflux and digestive discomfort, thanks to hormonal shifts and the pressure of a growing baby on the stomach. Traditional reflux treatments like PPIs aren’t always ideal for pregnant individuals, leading many to seek natural alternatives.

Probiotics, including Bifidobacterium lactis HN019 and Lactobacillus reuteri, have been studied for their effects on gut microbiome balance during pregnancy. Additionally, fermented food products like yogurt and kimchi can provide natural sources of beneficial bacteria.

The American Gastroenterological Association acknowledges the role of probiotic supplementation in supporting digestive health during pregnancy, but recommends consulting a healthcare provider before making dietary changes.

Bioma Probiotics: A Smart Choice for Digestive Health

Gut health is deeply connected to acid reflux, metabolism, and overall well-being. Bioma Probiotics offer a blend of clinically researched strains designed to support digestive health, gut microbiome balance, and acid reflux relief.

Key benefits include:

  • Targeted probiotic strains that promote digestive harmony and combat H. pylori-related reflux issues.
  • Prebiotics that nourish good bacteria and support a healthy gut lining.
  • Protection against dysbiosis, particularly for those using PPIs.
  • Potential weight support benefits, as a balanced gut microbiome plays a role in body composition and metabolic health.

Adding Bioma Probiotics to your routine may help manage reflux symptoms, restore gut balance, and promote long-term digestive wellness.

Additional Ways to Manage Acid Reflux

While probiotics can support gut health, they work best when combined with dietary and lifestyle changes. Here are a few tips:

  • Incorporate probiotic-rich foods like yogurt, kefir, kimchi, and sauerkraut.
  • Avoid large meals before bed, as lying down can worsen reflux symptoms.
  • Limit intake of trigger foods, such as spicy foods, fried foods, and caffeine.
  • Maintain a healthy weight, as excess fat can push stomach acid into the esophagus.
  • Elevate your head while sleeping to prevent acid from traveling upward.

A study published in The Journal of Gastroenterology and Hepatology found that individuals who combined probiotic supplementation with lifestyle modifications had significantly better reflux management than those relying on PPIs alone (source).

Are There Any Risks?

Probiotics are generally safe, but some individuals may experience temporary bloating, flatulence, or mild digestive discomfort when first introducing them. In rare cases, those with severe underlying conditions should consult a healthcare provider before starting probiotic therapy.

Potential risks include:

  • Allergic reactions to specific bacterial strains
  • Microbial dysbiosis from unbalanced probiotic supplementation
  • Interactions with antibiotic therapy, which can alter the effects of probiotics

Despite these considerations, research from The World Journal of Gastroenterology suggests that the right probiotic strain and dosage can make a meaningful difference in gut health without causing adverse effects.

Conclusion

Probiotics are showing real promise as a complementary approach to acid reflux management. While they may not replace traditional GERD treatments, research suggests that strains like Lactobacillus acidophilus, Bifidobacterium lactis, and Saccharomyces boulardii can improve gut microbiome balance, reduce gastric inflammation, and support digestion—all factors that influence acid reflux.

For those looking to go beyond medications and support long-term gut health, Bioma Probiotics offer a scientifically backed solution. Incorporating probiotics alongside lifestyle modifications and dietary changes may be the key to lasting relief from acid reflux and improved digestive wellness.

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